Levomycetin in cystitis: instructions for use, contraindications and analogues

Levomycetin in cystitis: instructions for use, contraindications and analogues

Cystitis is an infectious-inflammatory disease of the walls of the bladder, which is often caused by bacteria. The disease is characterized by such unpleasant symptoms as fever, difficulty or frequent urination, cutting pains in the lower abdomen, worsening of the general condition. For the treatment of pathology used a number of drugs, among which an important role is played by antibacterial agents. To eliminate the signs of inflammation, it is often prescribed for cystitis Levomycetin.

The content of the article

  • Characteristics of the drug
    • Substance class
    • Mechanism of action
    • Forms of release
    • Pharmacokinetics and pharmacodynamics
  • Indications
  • How to use with cystitis
  • special instructions
  • Contraindications
  • Side effects
  • Overdose
  • Analogs
  • Reviews
  • Video

Characteristics of the drug

Substance class

The drug is a broad-spectrum antibiotic of the chloramphenicol group, which is active against pathogenic microflora, causing the development of infectious diseases in various tissues and organs.

Mechanism of action

The drug has an antibacterial effect. Levomitsetin fights against pathogenic and conditionally pathogenic microorganisms that cause infection. The tool inhibits the development of the inflammatory process and eliminates the infection in the organs where it has developed. For example, if bacteria enter the urinary tract, cystitis or urethritis develops. The drug has activity without being tied to a specific organ, therefore, the pathogens will be destroyed regardless of where they are located.

The active substance contained in the preparation, chloramphenicol, is effective in the case when the pathogenic flora is insensitive to preparations of the penicillin and tetracycline groups.

The resistance of pathogenic bacteria to a drug develops very slowly, so in most cases it turns out to be effective.

Forms of release

The composition of the drug includes the active ingredient – chloramphenicol and additional components, depending on the form of the drug.

The drug is produced in the following forms:

  • tablets of a round form, yellow color, without cover, with bitter taste;
  • eye drops;
  • alcohol solution for external use;
  • liniment.

Pharmacokinetics and pharmacodynamics

Levomycetin has a bacteriostatic effect. The active ingredient is active against most gram-positive and gram-negative bacteria, causative agents of dysentery, typhoid fever and purulent infections.

In a therapeutic dose, it helps cure diseases caused by:

  • streptococci;
  • chlamydia;
  • rickettsia;
  • Brucella;
  • spirochetes; leptospira;
  • shigella.

The drug exhibits weak activity against acid-resistant bacteria and clostridia. Levomycetin in cystitis in women is ineffective if the disease develops as a result of the action of simple microorganisms or fungal damage.

The action of the drug is associated with the ability of the active component to disrupt protein synthesis and block the polymerization of activated amino acid residues that are associated with m-RNA.

After application, the active substance is rapidly absorbed by the mucous surface of the stomach. The highest concentration is observed in 1-3 hours after administration in the liver, kidneys, bile, cerebrospinal fluid and lasts about 6 hours. Chloramphenicol passes through the placental barrier and into breast milk.

The main amount of the active substance is metabolized in the liver and intestines. A day later, the remnants of drugs excreted by the kidneys and intestines.


Levomitsetin is used in the treatment of inflammation of the bladder of infectious origin.

The drug is prescribed for the treatment of diseases caused by microorganisms sensitive to the antibacterial agent:

  • inflammation of the abdominal cavity;
  • typhoid fever, salmonellosis;
  • urethritis, purulent inflammation of the urinary tract;
  • tick-borne ehrlichiosis;
  • prostatitis;
  • meningococcal infections;
  • venereal lymphogranuloma;
  • chlamydia;
  • tularemia;
  • brucellosis;
  • eye diseases of infectious origin: conjunctivitis, blepharitis, keratitis;
  • skin diseases: furunculosis, pressure sores;
  • infected burns;
  • trophic ulcers;
  • purulent otitis.

How to use with cystitis

Levomycetin in cystitis should be taken orally. In severe disease, intramuscular injections or intravenous fluids are indicated.

According to the instructions, take pills 30 minutes before meals, without chewing, drinking water. If the medicine causes nausea, it should be taken an hour after meals. Chloramphenicol is drunk three times a day, long-acting medication is taken twice.

The exact dosage is selected by the doctor individually for each patient, taking into account his condition and the severity of the disease. A single dose is 0.25–0.5 g. The daily dosage should not exceed 2 g. In severe forms of the disease, it can be increased pharma steroids to 4 g.

Duration of treatment is from 7 to 10 days. If necessary, it can be extended to 15-20 days. Do not take medicine for less than 7 days, because this time is not enough to destroy all the bacteria. The remaining pathogens do not have time to develop resistance to the active substance, and with repeated treatment it will not bring results.

Levomycetin in cystitis during pregnancy in a woman and during breastfeeding is used as prescribed by a doctor, since there are no data from clinical studies on the effect of the drug on an unborn child. Chlorfeminicol is able to penetrate into breast milk, so if necessary, treatment of the child should be transferred to artificial feeding. This will help avoid negative effects on the children’s body.

special instructions

The drug is used strictly as prescribed by a doctor at the indicated dosage, since Levomycetin affects all organs. It is not recommended to voluntarily increase the dose, as this will not bring a positive result.

The drug weakens the effect of contraceptives.

Pyrazolone, Phenobarbital, Ristomycin, Cimetidine, sulfonamides and cytotoxic agents are not used with an antibiotic.

Levomitsetin enhances the therapeutic effect of hypoglycemic drugs.

Joint reception with Paracetamol reduces the period of elimination of the antibiotic from the body, and therefore reduces its therapeutic effect.

The effectiveness of the drug is reduced when combined with phenytoin, cyclosporine, cyclophosphamide, and other means of this pharmacological group.

During treatment medication should stop drinking.


Treatment of inflammatory levomycetinum is not always possible.

The drug is not suitable if the patient has the following diseases:

  • increased hypersensitivity to the individual components of the drug;
  • violation of the function of the blood;
  • acute porphyria;
  • chronic liver disease;
  • renal failure;
  • malignant neoplasms;
  • fungal skin diseases;
  • psoriasis;
  • extensive wounds.

Side effects

Prolonged use of the drug may cause side effects.

Patients noted:

  • nausea;
  • vomiting;
  • loss of appetite;
  • weight loss;
  • violation of the chair;
  • increased gas formation.

Patients have signs of mental disorder, depression or irritability, increased anxiety, impaired consciousness and taste, headaches and dizziness, reduced hearing and sight.

Perhaps the development of dermatitis, fungal diseases, thrombocytopenia, agranulocytosis, hypohemoglobinemia, aplastic anemia.


An independent increase in the dose leads to the development of signs of overdose. In this case, the patients have symptoms of intoxication, which is accompanied by pale skin, sore throat, hyperthermia, bleeding, and general weakness.

At the first Buy steroids in USA sign of an overdose, flush the stomach, induce vomiting and seek qualified medical attention.


If antibiotic treatment does not bring positive results, you should contact your doctor, who will replace Levomycetinum with a similar means.

Currently, the modern pharmaceutical industry offers a wide range of drugs that have a similar effect and have a similar composition.

Levomycetin Actititab is a direct analogue, having an identical composition, but with a wider spectrum of action. The tablets have an oblong shape and are covered with an enteric coating. They do not have the bitter taste characteristic of the habitual Levomitsetina.

The following drugs have a similar effect:

  • Nolitsin;
  • Syntomycin;
  • Amoxiclav;
  • Monural;
  • Cefuroxime;
  • Furadonin.

You should not choose an analogue yourself, as this may adversely affect the state of the body and lead to irreversible consequences.


Very good and affordable tool. After a course of treatment for cystitis, there was no relapse. If you precisely follow the dosage, there is no side effect. To restore the intestinal flora, together with the pill, she took prebiotics.

Irina, 30 years old (Moscow)

A few years ago, she first fell ill with cystitis. Used for the treatment of folk remedies, herbal. After another exacerbation, she turned to a doctor who prescribed Levomycetin. The condition improved after 2 days. The drug is really very good.

Evgenia, 29 years old (Kaliningrad)

For a long time I suffer from chronic cystitis. The doctor recommended taking Levomitsetin. The drug acts very quickly, without a side effect. I take vitamins and painkillers with an antibiotic. Pleases the low price of medication.

Tatiana, 30 years old (Kaluga)


From this video you will learn about the indications and rules for taking Levomycetin tablets.

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